ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE
About
ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE is a combination medicine indicated to treat and prevent migraine. ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE is used to relieve the symptoms at the first sign of a migraine attack and to prevent the worsening of the attack. Migraine is a neurological condition that is characterized by an intense pulsating, throbbing, pounding, debilitating headache which usually occurs on one side of the head; however, it can occur on both sides or shift.
ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE is a combination of four drugs, namely: Ergotamine tartrate (ergot alkaloid), caffeine (methylxanthine), prochlorperazine maleate (anti-emetic) and paracetamol (analgesic). Ergotamine tartrate works by narrowing the blood vessels in the brain and affects the blood flow patterns associated with headaches. Caffeine enhances the vasoconstrictive effect (narrowing of blood vessels). Prochlorperazine maleate prevents nausea and vomiting associated with migraine by modifying the effects of neurotransmitters. Paracetamol blocks the release of prostaglandins that cause pain.
Take ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE with or without food. Swallow ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE as a whole with a glass of water; do not chew, or break the tablet. Take ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as stomach upset, dizziness, dry mouth, constipation, and insomnia (trouble sleeping). Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE contains paracetamol, do not take other medicines containing paracetamol along with ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE. Do not take ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE if you are pregnant or breastfeeding. ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE causes drowsiness and dizziness, so drive with caution. ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and ongoing medicines to rule out any side effects.
Uses of ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE
Medicinal Benefits
ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE contains Ergotamine tartrate, caffeine, prochlorperazine maleate, and paracetamol. ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE is used to treat and prevent migraines. Ergotamine tartrate is an ergot alkaloid that works by constricting blood vessels in the brain and altering blood flow patterns associated with headaches. Caffeine is a methylxanthine that increases the vasoconstriction effect (narrowing of blood vessels). Prochlorperazine maleate is an anti-emetic that prevents migraine-related nausea and vomiting by altering the effects of neurotransmitters. Paracetamol is an analgesic that prevents the release of prostaglandins, which cause pain. ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE is used to relieve migraine symptoms and prevent the attack from worsening.
Directions for Use
Storage
Side Effects of ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE
- Stomach upset
- Dizziness
- Dry mouth
- Constipation
- Insomnia (trouble sleeping)
In-Depth Precautions and Warning
Drug Warnings
Do not take ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE if you are allergic to any of its contents; if you have/had heart problems, blood circulation problems, or if you are taking antibiotics, anti-fungal, anti-HIV, or other anti-migraine medicines. ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE, when taken along with antibiotics, anti-fungal, and anti-HIV drugs, could lead to unpleasant side effects such as poor blood flow to hands, feet, or brain. ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE contains paracetamol, do not take other medicines containing paracetamol along with ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE. Inform your doctor before taking ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE if you have or had high blood pressure, heart problems, high cholesterol, diabetes, asthma, liver and kidney problems. Do not take ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE if you are pregnant or breastfeeding. ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE may cause drowsiness and dizziness, so drive only if you are alert. ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol along with ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE as it could lead to increased drowsiness. Do not take other NSAIDs for pain relief while taking ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE unless prescribed.
Drug Interactions
Drug-Drug Interactions: ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE may have interaction with antibiotics (clarithromycin, erythromycin, troleandomycin), anti-fungal (itraconazole, ketoconazole), and anti-HIV medicines (indinavir, nelfinavir, ritonavir), a decongestant (oxymetazoline), pain killers (acetaminophen, butalbital, fentanyl), anti-depressant (fluoxetine, duloxetine), anti-anxiety (diazepam, lorazepam, alprazolam), antacid (ranitidine), antihistamine (diphenhydramine), anti-convulsant (pregabalin), anti-hypertensive (metoprolol), bronchodilators (albuterol), anti-emetic (ondansetron).
Drug-Food Interactions: Avoid the consumption of alcohol, smoking, and caffeinated products. Do not consume grapefruit while taking ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE.
Drug-Disease Interactions: ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE may have interactions with high blood pressure, vasospastic reactions, heart problems, bipolar disorder, psychotic disorders, seizure disorders, gastroesophageal reflux disease, and liver or kidney problems.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consumption of alcohol while taking ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE as it may increase drowsiness.
Pregnancy
unsafeERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE is not recommended for use in pregnancy. If you are pregnant or planning pregnancy, inform your doctor before taking this medicine.
Breast Feeding
cautionIf you are breastfeeding, inform your doctor before taking this medicine. Your doctor may prescribe this medicine if the benefits outweigh the risks.
Driving
cautionERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.
Liver
cautionDose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.
Kidney
cautionDose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
unsafeERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE should not be given to children as safety and effectiveness were not established.
Habit Forming
Diet & Lifestyle Advise
- Maintaining a healthy diet and exercising regularly helps improve overall health and boost self-esteem.
- Avoid bright lights, loud noise, and extreme temperatures.
- Perform meditation and yoga. This helps in relieving stress and provides relaxation.
- Follow a regular sleep pattern to improve the amount and quality of sleep you get.
- Massage your scalp to ease the pain.
- Lie down in a quiet, dark room.
- Place a cold cloth over your forehead or neck.
- Avoid smoking, alcohol, and caffeinated drinks.
- Learn what triggers your migraine and try avoiding them.
- Stay hydrated. Drink plenty of fluids.
- Learn relaxation skills as they help in reducing stress.
Patients Concern
Disease/Condition Glossary
Migraine: Migraine is a neurological condition that is characterized by an intense, debilitating headache. Hormonal changes, stress, lack or excess of sleep, bright lights, loud sounds, and certain foods and drinks can trigger migraine headaches. A migraine headache is preceded by warning symptoms one or two days before the headache. The warning symptoms include food cravings, depression, fatigue, hyperactivity, irritability, and neck stiffness. Symptoms of migraine include throbbing pain in one particular area with varying intensity, nausea, vomiting, numbness or tingling sensation, difficulty speaking, and sensitivity to sound and light.
FAQs
ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE contains Ergotamine tartrate, caffeine, prochlorperazine maleate, and paracetamol. Ergotamine tartrate works by narrowing the blood vessels in the brain and also affects the blood flow patterns associated with headaches. Caffeine enhances the vasoconstrictive effect (narrowing of blood vessels). Prochlorperazine maleate prevents nausea and vomiting associated with migraine by modifying the effects of neurotransmitters. Paracetamol blocks the release of prostaglandins that cause pain.
Dry mouth could be a side effect of ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might help stimulate saliva and thereby prevent drying of the mouth.
Orthostatic hypotension could be a side-effect of ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE. Orthostatic hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead, lie down and get up slowly only when you feel better. People taking ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE are advised to monitor their blood pressure levels regularly to avoid such unpleasant events.
Do not discontinue ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE without consulting your doctor, as it could lead to recurring or worsening of symptoms. To treat your condition effectually, continue taking ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE.
Do not take ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE along with antibiotics (clarithromycin, erythromycin, troleandomycin), anti-fungal (itraconazole, ketoconazole) and anti-HIV medicines (indinavir, nelfinavir, ritonavir). ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE contains ergotamine and caffeine, which, when taken along with these drugs, could lead to unpleasant side effects such as poor blood flow to the hands, feet, or brain.
ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE may cause constipation. Eat high-fibre foods and drink plenty of fluids if you experience constipation. Talk to your doctor if you have severe constipation.
Available Medicines for
ERGOTAMINE TARTRATE+CAFFEINE+PARACETAMOL+PROCHLORPERAZINE MALEATE
